The obvious response here is that if MPG and running costs are a consideration, then the LC 500h is the better bet. The hybrid will achieve around 35mpg depending on its driving environment, with the V8 some 10mpg off that figure. Drive gently with either and these figures are achievable mind, and thanks to its lack of forced induction, driven hard those figures won’t drop quite as dramatically as others.
If build quality and reliability are a big draw than Lexus's typically flawless record is no different despite the LC's exotic image, with reliability of the 2UR V8 engine noted in all its global applications be that in a Lexus saloon in the USA or body-on-frame SUV in the Middle East. Parts pricing is therefore reasonable, and the engine's relative simplicity also helps in this regard.